Impact of electronic cigarette use on blood pressure: A systematic review ScienceDirect The use of vapes and e cigarettes causes an immediate increase in blood pressure, heart rate, and blood vessel constriction. In the long run, this can cause an increased risk for heart disease. Electronic Nicotine Delivery Systems (ENDS), including e cigarettes and vapes, are often perceived as a safer alternative to traditional tobacco. But is the evidence really supporting this belief? A recent umbrella review published Does Vaping Cause High Blood Pressure? EDGE Vaping Vaping Versus Smoking: Are Electronic Cigarettes the Savior? Arteriosclerosis, Thrombosis, and Vascular Biology