Health effects of electronic cigarettes Wikipedia E cigarettes contain hazardous substances, addictive and harmful Since their introduction in Europe in 2006 and the U.S. in 2007, the use of e cigarettes a.k.a., vapes has skyrocketed. A recent review from researchers in Australia found the results Vapes, pouches, heated tobacco, shisha, cigarettes: nicotine in all forms is toxic to the heart and blood vessels Experts call for Europe wide action to stem new wave of youth addiction https: academic.oup.com eurheartj advance article doi 10.1093 Frontiers Direct health implications of e cigarette use: a systematic scoping review with evidence assessment